EFFECT OF NYPA FRUTICANS STEM AND LEAF EXTRACT ON GLUCOSE TOLERANCE IN GLUCOSE-INDUCED HYPERGLYCEMIC MICE
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| Title | EFFECT OF NYPA FRUTICANS STEM AND LEAF EXTRACT ON GLUCOSE TOLERANCE IN GLUCOSE-INDUCED HYPERGLYCEMIC MICE |
| Authors | |
| Abstract | Nypa fruticans (Thunb.) Wurmb. (Palmae), also known as Golpata in Bangladesh, is the only palm considered a mangrove. In this study, we examined the effect of methanol extract of stems and leaves on serum glucose lowering ability in glucose-induced hyperglycemic mice (glucose tolerance test). Fasted mice were divided into five groups. Group 1 (control) received distilled water. Groups 2-4 received methanol extract at oral doses of 100, 250 and 500 mg/kg body weight (bw). Group 5 received glibenclamide at an oral dose of 10 mg/kg bw. After 60 min of extract administration, the mice of all groups were orally treated with 2 g/kg bw of glucose. Blood samples were collected at 60 and 120 min after glucose loading and serum glucose levels determined. The significance of the results was calculated using Student’s t-test and were considered statistically significant when P |
| Publisher | African Ethnomedicines Network |
| Date | 2009-06-07 |
| Source | African Journal of Traditional, Complementary and Alternative medicines (AJTCAM) ABSTRACTS OF THE WORLD CONGRESS ON MEDICINAL AND AROMATIC PLANTS, CAPE TOWN NOVEMBER 2008 |
| Rights | Articles can be used for educational and non-comercial purposes. The copyrights of articles are retained by the authors with publication rights granted to AJTCAM. |