BIOCHEMICAL AND TOXICOLOGICAL EFFECTS OF GLOBIMETULA BRAUNII (LORANTHACEAE) LEAF
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| Title | BIOCHEMICAL AND TOXICOLOGICAL EFFECTS OF GLOBIMETULA BRAUNII (LORANTHACEAE) LEAF |
| Authors | |
| Abstract | Globimetula braunii (Engle) Van Tiegh, growing on the Cola acuminata tree is used in Nigerian traditional medicine as a laxative, against diabetes, as an antihypertensive and as an antimicrobial agent. Information on biological activity of this plant is scanty, however previous studies have reported the antidiabetic (Olagunju et al., 1999)) and laxative effects (Fred-Jaiyesimi et al., 2008) of the leaf. This study aims at investigating the biochemistry and safety of the ethanol extract of Globimetula braunii leaf by determining its pharmaco-toxicological effects after administration in rats. After administering the extract to rats for 14 days, no deaths occurred. A single daily oral administration of G. braunii ethanol extract (2 g/kg) significantly (p |
| Publisher | African Ethnomedicines Network |
| Date | 2009-06-07 |
| Source | African Journal of Traditional, Complementary and Alternative medicines (AJTCAM) ABSTRACTS OF THE WORLD CONGRESS ON MEDICINAL AND AROMATIC PLANTS, CAPE TOWN NOVEMBER 2008 |
| Rights | Articles can be used for educational and non-comercial purposes. The copyrights of articles are retained by the authors with publication rights granted to AJTCAM. |