Thrombocytopenia With Valproate And Clozapine Combination Therapy
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| Title | Thrombocytopenia With Valproate And Clozapine Combination Therapy |
| Authors | |
| Abstract | Objective: The occurrence of thrombocytopenia with valproate and clozapine combination therapy has not been noted in the literature. This case report highlights thrombocytopenia as a potential outcome of drug-drug interaction between valproate and clozapine, and serves to remind practitioners that regular monitoring of platelet counts is necessary in such combination therapy. Method: We report on a patient on valproate therapy who developed thrombocytopenia when clozapine was added to her treatment regime. Results: Thrombocytopenia resolved 1 week after valproate was tailed off and the patient was placed on clozapine monotherapy. |
| Publisher | ASEAN Federation of Psychiatry and Mental Health (AFPMH) |
| Date | 2011-07-14 |
| Source | ASEAN Journal of Psychiatry Vol 12, No 1 (2011): ASEAN Journal of Psychiatry |