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FREQUENCY OF THROMBOCYTOPENIA IN PREGNANCY RELATED HYPERTENSIVE DISORDERS IN PATIENTS PRESENTING AT TERTIARY CARE HOSPITALS OF PESHAWAR
Journal Title Khyber Medical University Journal
Journal Abbreviation KMJ
Publisher Group Kohat University of Science and Technology (KUST)
Website http://www.kmuj.kmu.edu.pk
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Title FREQUENCY OF THROMBOCYTOPENIA IN PREGNANCY RELATED HYPERTENSIVE DISORDERS IN PATIENTS PRESENTING AT TERTIARY CARE HOSPITALS OF PESHAWAR
Authors nazli, Rubina; khan, Mohammad Akmal; akhtar, Tasleem; Mohammad, Nabila Sher; aslam, Hina; haider, Jamila
Abstract ABSTRACT Objective: To find the frequency of thrombocytopenia in women with pregnancy related hypertensive disorders inpatients presenting at tertiary care hospitals of Peshawar.Methodology: This cross sectional study was conducted from January 2009 to January 2010 in the tertiary referralhealth care facilities of Peshawar. A total of 312 women of gestational age of >20 weeks with pregnancy relatedhypertensive disorders were investigated. They were subdivided into 102 women with gestational hypertension (GroupA), 100 women with pre-eclampsia (Group B), and 110 women with eclampsia (Group C). Ninety healthy pregnantwomen (group D) were chosen as control. All the subjects were selected from the Gynecology and Obstetrics units ofthree tertiary health care facilities of Peshawar. Platelet count was measured by using Hematology Analyzer. The datawas processed on SPSS version 10.Results: The frequency of thrombocytopenia in all patient groups was 21.8% (n=68/312). Individual groups showedthrombocytopenia in 14.6% (Group A), 15% (group B), 34.6% (group C) and 4.5% in controls (group D). Out of 68patients with thrombocytopenia, 38(55.9%) were eclamptic. Overall severe thrombocytopenia was recorded in 27(8.7%)patients, of whom 15(55.6%) were eclamptic. These patients were nine times more likely to have eclampsia as comparedto those having platelet count > 150,000/μL (OR: 9.41; CI: 1.33-188.8; p= 0.008).Conclusion: A high frequency of thrombocytopenia was recorded in the patients with pregnancy related hypertensivedisorders in the tertiary care hospitals of Peshawar. The severity of thrombocytopenia is proportional to the severity ofpregnancy related hypertensive disorders.Key Words: Pregnancy Related Hypertensive Disorders; Platelet Count; Thrombocytopenia; Gestational Hypertension,Pre-Eclampsia.
Publisher KMU Institute of Medical Sciences (KIMS)
Date 2013-03-10
Source Khyber Medical University Journal Vol 4, No 3 (2012): Khyber Med Univ J 2012
Rights Upon acceptance by KMUJ, all copyright ownership for the article is transferred to KMUJ.Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work

 

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