INVESTIGATION OF THE ROLE OF PLACENTA IN TRANSFER OF BROMINE CONTAINING DRUGS TO INFANTS
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| Title | INVESTIGATION OF THE ROLE OF PLACENTA IN TRANSFER OF BROMINE CONTAINING DRUGS TO INFANTS |
| Authors | |
| Abstract | A study was undertaken to investigate the role of placenta in transferring drugs containing bromine to the infant. 20 pregnant subjects were given bromine as KBr (500 mg/50 Kg weight) 10h before the delivery the bromine content of the serum in the mother and the child was estimated by neutron.. 13 lrradlated at 2xlO activation analysis. Samples were -2 -1 n em 5 for a period of one hour. A Ge (Li) detector connected to an 800 channel analyser 82 was used for measuring Br photopeaks. In 72% of the cases the distribution of bromine in both mother and child was equal, revealing a transfer across the placenta of the intaken drug. |
| Publisher | Tehran University of Medical Sciences |
| Date | 2012-10-20 |
| Source | Acta Medica Iranica Vol 22, No 3 (1980) |