GLYCOSIDASES IN HUMAN BLOOD PLASMA AND URINE. MOLECULAR FORMS AND ACTIVITY LEVELS
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| Title | GLYCOSIDASES IN HUMAN BLOOD PLASMA AND URINE. MOLECULAR FORMS AND ACTIVITY LEVELS |
| Authors | |
| Abstract | The isoe lect r i c f ocusing p a t terns and pH activity cur ves of f i ve glycosidas e e nzymes i n blood plasma and ur i ne were s t ud i e d . This s tudy demons trated the presence o f a sing le molecular f onn in a -glucosidase and of two mole cul a r fonns of the enzymes H-a ce t yl-B-D-gluco sarni nidase, Na c e t y l -•p-D-g a l a c t o s amin i ua s e and S-glucuronidase i n both plasma and urine . B-Galactosidase existed as a s i ng le major molecular f orm i n p l asma and a t l e a st t wo molecular forms in urine. Spe cific activity of each~ le n zyme was determined in p lasma and urine The validity o f taking the ratio between two e n zvrne activities as an index for scr een .l.ng of fr ene t ic di s e a s e is discussed. |
| Publisher | Tehran University of Medical Sciences |
| Date | 2012-10-20 |
| Source | Acta Medica Iranica Vol 24, No 1-2 (1982) |