The effect of Lead Acetate on the Nitric Oxide system in the rat Hippocampal cells: An in-vitro study
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| Title | The effect of Lead Acetate on the Nitric Oxide system in the rat Hippocampal cells: An in-vitro study |
| Authors | |
| Abstract | The mechanism by which lead may cause a perturbotion in the nevous system is through the nitric oxide synthase. In this study the effect of lead acetate on the hippocampal constitutive nitric oxide production was studied. The variation in the nitric oxide production may contribute to physiological lead neurotoxicity in vivo. Different concentrations of lead acetate (10-9 to 10-6 M), wre added to cultures of hippocampal pyramidal cell obtained from one-day newborn rats. Sodium acetate was used as control. In this range of stuy viability of cells did not alter when it was compared to control (P |
| Publisher | Tehran University of Medical Sciences |
| Date | 2012-10-20 |
| Source | Acta Medica Iranica Vol 39, No 1 (2001) |