AMPHOTERICIN B AND NEONATAL SYSTEMIC CANDIDIASIS
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| Title | AMPHOTERICIN B AND NEONATAL SYSTEMIC CANDIDIASIS |
| Authors | |
| Abstract | Systemic candidiasis i" a major problem in high risk neonates. Mortality is high but may be reduced by prompt antifungal therapy.Y> c administered amphotericin li to 22 infants lift preterm with imtin birti´ weigh: < ISOOg; mean gestational age .t2 i 2 weeks} tun! 4 full term newborn (mean birth weith, MIX- z. 200g. mean gestational age, .M ± .i weeks) infant;. with systeoiii candidiasis. During the IO year period. 22 infants wiln systemic Candida! infection were identified. Ill males and 12 female Within 5 days of starting therapy. 3 infants died I nun overwhelming and severe multisystem involvement, including centra; nervous system Candida infection. Altnoiu-h amphotericin B´ may have contributed to the death of -> infants, ovens-helming disseminated Candida infection was the more likely cause. Our experience supports the opinion that infants taurnic amphotericin H well. |
| Publisher | Tehran University of Medical Sciences |
| Date | 2012-10-20 |
| Source | Acta Medica Iranica Vol 37, No 3 (1999) |