Journal Title Acta Medica Iranica Journal Abbreviation acta Publisher Group Tehran University of Medical Sciences (TUMS) Website http://acta.tums.ac.ir

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Title	RESULTS OF ALLOGENIC BONE MARROW TRANSPLANTATION IN CML IN IRAN
Authors	A. khodabeh., ; P.Nasseri., ; M Jahani., ; A.Ghavamzadeh., ; I. Baybordi., ; M. Mohyeddin. G. Ghahremani,
Abstract	Nineteen patterns with CML have been transplanted in our Bone Marrow Transplantation (BMT) section since 1991, The mean age of these patients was 26.05 (SD = 9.35). Our conditioning regimen for these patients was cyclophosphamide 60mglkg for 2 days and busulfan 4mglkg for 4 consecutive days. Eleven patients are still alive arid eight patients died during follow-up ranging from 6 months to 5 years. This review revealed a poor outcome for patients older than 30. There was also a rise in the mortality rate when the interval between diagnosis and BMT was longer than 2 years. In contrast with some previous reports, we found no relationship between spleen size in the pre-transplant period and BMT outcome, however recurrence of CM L after BMT correlates strongly with spleen size (P<0.t)01). Cellular recovery (WBC > 1000/ml, PMN > 5001ml. PLT > 1000001ml) correlates directly with spleen size as well (P<0,05).
Publisher	Tehran University of Medical Sciences
Date	2012-10-20
Source	Acta Medica Iranica Vol 36, No 1 (1998)

 

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