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FETAL ALCOHOL SYNDROME IN FETUS OF MOUSE
Journal Title Acta Medica Iranica
Journal Abbreviation acta
Publisher Group Tehran University of Medical Sciences (TUMS)
Website http://acta.tums.ac.ir
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Title FETAL ALCOHOL SYNDROME IN FETUS OF MOUSE
Authors B. Nasrollahzadeh, ; M. Heshmati,
Abstract litis study is based on embryotoxic effects of ethanol on embryos and discussing the morphologic and hhtahtgic changes and defects an mouse. Tlie female animals were divided in three groups. Hie first group untreated as a control group but the second and third group received 10% and 20% solutions of ethanol respectively. Animals get use to certain level of ethanol solution and in the 10th day, the pregnancy period has been started. Then on the 19th day of gestation, the embryos were taken out from their mother´s uterus and were examined for morphologic, histologic and skeletal disorders. In the first examination, the major defect was weight and length reduction in the second and third groups. these deffects, were severe in the second group in compare to third group that might be related to little consumption of the ethanol solution, due to bitter taste. In conclusion the teratogenic effect of alcohol on skeleton and joint is clear.
Publisher Tehran University of Medical Sciences
Date 2012-10-20
Source Acta Medica Iranica Vol 35, No 3-4 (1997)

 

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