IMBALANCE OF T-CELL SUBSETS IN IRANIAN ALLERGIC RHINITIS PATIENTS
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| Title | IMBALANCE OF T-CELL SUBSETS IN IRANIAN ALLERGIC RHINITIS PATIENTS |
| Authors | |
| Abstract | r´Iwenty-nine patients were studied to determine the number of CJ).j+ Tscell subsets in Iranian allergic rhinitis patients. The result was compared with that a/twenty-four nonatopic controls. The number of11 and CDS+T cell´)and levels ofspeafic IgE and /g(;4 against weed pollens were also studied The number of lymphocyte subset, tltat is, CD-/+ C/)29+and C1Jf CJ)451t cells were determined hy doublelabeling immunofluorescence assay. The results showed that the number ofClJ-I+ CD.f.5It cells to; significantly higher in the patients (626 ± 251.-1cell´)per one micro/iter ofperipheral blood) than in control subjects (479A ± 78.2 cell per one microliter) (P <().05). However, there WlLf no statistical difference between the number oJCJ).f+ CD29+cells in the tH´O groups. There were no correlation between the number of CD.f CD.f5It cells ill tlte peripheral blood of allergic patients and levels of total and specific IgE, hut a direct correlation was found between tlte levels ofspecific IgE and specific IgG.j ill the sera oj allergic patients (r=O.55, P < 0.0(2). |
| Publisher | Tehran University of Medical Sciences |
| Date | 2012-10-20 |
| Source | Acta Medica Iranica Vol 33, No 3-4 (1995) |