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Antibacterial Activity of Crude Extracts of Marine Invertebrate Polyclinum madrasensis Sebastian
Journal Title Indian Journal of Science and Technology
Journal Abbreviation indjst
Publisher Group Informatics (India) Limited (gjeis)
Website http://gjeis.org/index.php/indjst
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Title Antibacterial Activity of Crude Extracts of Marine Invertebrate Polyclinum madrasensis Sebastian
Authors Natarajan, K.; Sathish, R.; Regupathi, T.; Riyaz, A.
Abstract Antibacterial activity of methanol, hexane and petroleum ether extracts of Polyclinum madrasensis was evaluated by cup plate method against various clinical isolates. Two different concentrations (1&4 mg/ml) were analyzed. Methanolic extract of P. madrasensis demonstrated high degree of activity against all tested bacterial isolates in increasing concentrations, whereas hexane extract showed good activity against gram negative pathogens in high concentration and moderate against gram positive pathogens in lower concentration. All strains were resistant to Pet ether extract in both the concentrations when compared to the standard (ciprofloxacin) used. The MIC and MBC for methanolic extract tested in study inferred that the values range between 0.70-0.95 mg/ml and 0.85-1.1 mg/ml respectively. It was concluded from the study that methanolic extract of P. madrasensis exhibits potential antibacterial property.
Publisher Indian Society for Education and Environment (ISEE)
Date 2010-03-01
Source Indian Journal of Science and Technology Volume 3, Issue 3, March 2010

 

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