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Lipid Peroxidation and Antioxidant Status in Prostate Cancer Patients
Journal Title Indian Journal of Science and Technology
Journal Abbreviation indjst
Publisher Group Informatics (India) Limited (gjeis)
Website http://gjeis.org/index.php/indjst
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Title Lipid Peroxidation and Antioxidant Status in Prostate Cancer Patients
Authors Sandhya, B.; Manoharan, S.; Lavanya, G. Sirisha; Manmohan, Ch. Ratna
Abstract Objective: To assess the oxidative stress in plasma and erythrocytes of prostate cancer patients by measuring the levels of lipid peroxidation and antioxidants. Patients&methods: 20 newly diagnosed prostate cancer patients and an equal number of age between 55-70 years and sex matched normal subjects from Guntur, AP, India were chosen for the study. Biochemical parameters like TBARS, enzymatic antioxidants, non enzymatic antioxidants were analyzed and monitored in plasma and erythrocyte membranes of normal and prostate cancer patients. Results: The subjects were ranging in age from 55-70 years. Changes observed from baseline expressed as mean ±SD in plasma of normal and prostate cancer patients are TBARS 3.8±0.2, 6.9±0.52(PConclusion: The antioxidants and lipid peroxides levels in prostate cancer patients were altered when compared to normal patients. The picture of prostate cancer in India is potentially underestimated owing to scant data.
Publisher Indian Society for Education and Environment (ISEE)
Date 2010-01-01
Source Indian Journal of Science and Technology Volume 3, Issue 1, January 2010

 

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